Activ_Movie

A2a activation transition

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The movie shows conformational morphing  between inactive, antagonist bound (yellow) and active, agonist bound (orange) forms of A2Aa adenosine receptor.


Xu, F., Wu, H., Katritch, V., Han, G.W., Jacobson, K.A., Gao, Z.G., Cherezov, V. and R,C. Stevens. (2011) Structure of an agonist-bound human A2A adenosine receptor. Science Express, March 10 2011.


The files created using Molsoft ICM-Pro
and visualised using activeICM (Patent Pending).